Cailin Conner

Urban Health Today

The mean loss of life expectancy (LOLE) after myocardial infarction (MI) is higher in younger individuals, women, and those with reduced left ventricular ejection fraction (LVEF), according to a study in Circulation.&ldquo;The effect of MI on life expectancy is difficult to study because the prevalence of MI hinders direct comparison with the life expectancy of the general population,&rdquo; the investigators wrote. Thus, they conducted a registry-based matched cohort study to evaluate how MI impacts life expectancy in relation to age, sex, and LVEF.The study analyzed patients who had their first MI between 1991 and 2022 using data from the nationwide SWEDEHEART registry (Swedish Web-System for Enhancement and Development of Evidence-Based Care in Heart Disease Evaluated According to Recommended Therapies). MI patients (n=335,748) were matched with up to 5 controls (n=1,625,396) based on age, sex, and region of residence. Researchers employed flexible parametric survival models to estimate the excess mortality risk and the mean LOLE based on the index year, age, sex, and LVEF.The study found that LOLE was higher in younger individuals, women, and those with reduced LVEF (&lt;50%). Specifically, &ldquo;In 2022, the unadjusted and adjusted mean LOLE spanned from 11.1 and 9.5 years in 50-year-old women with reduced LVEF to 5.0 and 3.7 months in 80-year-old men with preserved LVEF. &ldquo;From 1992 to 2022, the adjusted mean LOLE decreased by 36% to 55%: from 4.4 to 2.0 years for 50-year-old women, from 3.3 to 1.9 years for 50-year-old men, from 1.7 to 1.0 years for 80-year-old women, and from 1.4 to 0.9 years for 80-year-old men.While the results showed LOLE to be higher among younger individuals, women, and those with reduced LVEF, the researchers emphasized that, when adjustments are made for comorbidities and risk factors, the impact is lessened. &ldquo;Advances in MI treatment during the past 30 years have almost halved LOLE, with no clear sign of leveling off to a plateau.&rdquo;Source: <a href="https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.124.068739" target="_blank" rel="noopener">Circulation</a>

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Women Lose More Years of Life After a Heart Attack Than Men, Research Finds

Heart Health

Myocardial infarction notably reduces life expectancy, especially in younger individuals and women, though treatment advances have nearly halved this effect over 30 years.

Women Lose More Years of Life After a Heart Attack Than Men, Research Finds 

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